grey, gray, blue, moms eyeshadow, Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time, The chance to concuss enemies is affected by your luck stat and at +27 Luck it will activate every time, * item room, treasure room, item room pool, grey, gray, silver, ingot. One of the sounds lasers can make when synergizing with Monstro's Lung. The split tears are affected normally by shot speed. This includes damage you deal, and environmental damage they take e.g. Based loosely on the Steam Workshop mod created by Extreme Ninja Home Makeover with changes by Edmund McMillen, *, lepracy, leprasy, leprosy, pink, red, bloody, lump, Gives you a random Harbinger familiar that changes every 10 seconds, Each harbinger behaves differently, based on any of the original 5 horsemen bosses, REPENTANCE - The harbingers will also randomly spawn their relevant Locust variant. Unlocked by beating Isaac with Samson. For example if the spawned boss leaves creep, it can damage Isaac, UNLOCK: Unlock this item by defeating Delirium for the first time on any character, A familiar fly that orbits around a random enemy in the room until that enemy dies, dealing 2 contact damage to other enemies, Angry Fly will move to the next enemy after the one it is currently orbiting dies, until the room is cleared, at which point it will return to orbiting Isaac, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Custom Phase, UNLOCK: Unlock this item by transforming into Beelzebub (Achieved by picking up 3 fly related items, see Transformations page for full list), A throwable active item that places a black hole on the ground where it lands, sucking all enemies into it for 6 seconds, Enemies stuck inside the black hole take rapid damage over time, The Black Hole will also suck Isaac into it, but with a much weaker effect than to enemies, The Black Hole will destroy nearby obstacles such as rocks and pots, Adds a random chance for an enemy in the current room to become charmed or feared briefly, Adds a random chance to spawn a rainbow poop upon taking damage, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Electoon, UNLOCK: Unlock this item by breaking 5 rainbow poops, *, red, white, stripe, hat, clown, waldo, wally, Causes random enemies to 'lag' at random intervals, causing them to freeze in place for a second, The lag effect can also apply to tears, projectiles and consumables on the ground, While held, this item has a 25% chance to double up any end of room drops (similar to the Contract from Below effect), Isaac's Luck stat affects how often the lag effect occurs, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Freezenification, UNLOCK: Complete 7 Daily Challenges (30 on console), A one-time use item that spawns a random item from the current room's item pool, with a chance for it to spawn Lump of Coal or The Poop instead, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Mills, *, green, red, present, bow, xmas, christmas, When used, spawns a Sprinkler that rotates in a circle, spraying tears in all directions, Will also synergize with some other items, such as Mom's Eye, Brimstone, Dr. Fetus, Tech X or Loki's Horns, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Kieran and Stewartisme, Allows you to rapidly place bombs on the ground, Added as part of the Afterbirth+ Booster Pack #1. Update 1.7.9b (9th Dec) changes have been added to the site, When used, copies the effect of the Rune or Soul stone you are holding (like the Blank Card), Drops a random rune on the floor when picked up. Item Pool or the path they take (My Reflection, Tiny Planet etc. When used, this card drops all of your hearts (including non-red hearts), coins, keys and bombs on the floor, This effect is done in the most efficient way possible - e.g. This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson, Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force, The effect lasts for 8 seconds but does persist between rooms, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel, When used this kills Isaac and revives him with 1/2 a red heart. UNLOCK: Unlock this trinket by defeating Greedier Mode with ??? It will attempt to hide behind you when shooting. Bosses Starts at +3.6 damage and goes to 0 after 30 seconds, While this temporary damage boost is active, each enemy you kill increases your damage slightly, allowing you to quickly kill multiple enemies and chain the effect for longer, This item also gives a -0.03 Speed Down for every food item held. The finger deals 10% of your normal damage to all enemies in the same direction that the finger is pointing, The finger will also deal damage to entities such as fires and poops, Applies on-hit status effects such as the burning debuff from Fire Mind, Spawns guppy flies if you have the Guppy transformation, Isaac gains a shadow familiar that will follow Isaac's movement pattern delayed by 1 second and deal 5 contact damage to enemies per tick, Shade is absorbed by Isaac after dealing 666 damage. All floors guaranteed to have an Arcade except the Chest & Dark Room floors, Judas - Gives a passive Book of Belial item similar to Book of Virtues. One of the sounds lasers can make when Isaac's tear size is large (or when damage is 10.0 or more). - Turns Isaac invincible for a few seconds (similar to Unicorn Stump). The charge direction now allows for a minor amount of control, * headless horseman, headless horsemen, red, grey, gray, A bag of bombs that will drop a bomb pickup every 2 rooms, UNLOCK: Unlock this item by beating Satan with Cain, * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, This may cause you to skip floors where you left a trinket to spawn a Cracked Key. Void tears that touch enemies will spawn Big Horn, who appears and grabs them, instantly killing that enemy, The chance to for each tear to become a void tear is affected by your luck stat and at +15 Luck it will activate 20% of the time, Isaac also grows a horn on his head, which causes you to deal contact damage to enemies by running into them (this effect deals base damage of 3.5 per tick), Void tears from this item can also destroy blue/purple fires, spiked blocks and stone grimaces, When used, will spawn a fly turret that doesn't move and fires tears at nearby enemies, The fly's bullets deal 3.5 damage each and do not scale with your own damage stat. Azazel is a playable character in The Binding of Isaac: Four Souls. yellow book how to, * boss room pool, boss room item, bone, red, brown, Gives Isaac a random tarot card when picked up, * boss room pool, boss room item, eight, grey, gray, Drops 4 random pills on the floor around Isaac, Item Pool: Shop, Boss Room, Challenge Room, Beggar, Demon Beggar, Mom's Chest, * dungeon room, blood challenge room, arena pool, demon beggar pool, demon judgement pool, devil beggar pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, shop room pool, shop item pool, bag, pouch, moms coin purse, mom coin purse. Health down effects still only remove 1 heart, Eve - Whore of Babylon and Dead Bird effects are always active, Samson - Bloody Lust can gain 4 more damage boosts, for a new max total of +14 Damage, Azazel - His beam becomes much wider, no effect on damage. The damage bonus is unaffected by both positive and negative damage multipliers. Incubus will not trigger the Brimstone ring. the lost item pool, purple, cross, Item Pool: Curse Room, Devil Room, Demon Beggar, * curse room pool, devil pool, devil room pool, devil deal, red, 666, Item Pool: Devil Room, Curse Room, Demon Beggar, * curse room pool, devil pool, devil room pool, devil deal, piece of paper, bloody paper, contract, Effects Does BFF affect rotten baby? in The Chest as Apollyon, Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage, UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon, At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it, UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon, When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room, UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel, Stem Cell heals Isaac's red heart containers to 50% each floor, If Isaac already has 50% health or more, it heals half of a heart instead, UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson, Fully recharges your active item at the start of each boss fight, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus, Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take, Does not recharge until the start of the next floor, Stacks with the effects from Holy Mantle and Blanket, but it does not stack with Holy Card, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills, Using your active item while holding this trinket will drop it back on a pedestal on the ground, Also after taking damage, you have a very small chance to drop one of your passive items, One-time use active items will be consumed and not dropped, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti, *, yellow, golden, box, block, square, cube, Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces, Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen, While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it, This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight, UNLOCK: Unlock this trinket by blowing up doors and secret room walls 50 times, *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis, After being picked up, a yellow laser chain now flows through Isaac's familiars, Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom, While held, spawns +1 friendly blue fly every time you pick up a coin, Added as part of the Afterbirth+ Booster Pack #5. Tears continue to fire from your left eye, The laser deals damage equal to 1/7th of your tear damage, but very rapidly, The laser can apply status effects (e.g. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. red, bolt, cupid arrow, cupids arrow, When used, fires a high damage laser in a straight line across the room in a similar way to Brimstone, The laser deals damage equal to double your tear damage. Pills with effects that can't necessarily 'double' are stronger, i.e. . Modes Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms, Can move any of the following: Batteries, Items, Trinkets, Hearts, Keys, Bombs, Coins, Chests and more, Using Moving Box with Car Battery will trigger 2 interactions at the same time: First it will drop all items currently inside the box and secondly will then pick up the current room's contents, When used in a room with 2 items you can choose from (e.g. Rooms Collection Grid Teratoma, Envy) then Meat Cleaver will deal a lot of damage and trigger the splitting effect, If the split enemy has low enough health, it will just die instead of splitting, Doesn't work on end-game bosses except Delirium, where it will deal a chunk of damage and spawn a 2nd Delirium to deal with, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Isaac, You no longer take damage from poison/toxic gas/burn effects, and become immune to fear/confusion, This item isn't available in any item pools - you are automatically given it after defeating Dogma, just before The Beast sequence, Grants a one-time use of the Holy Mantle effect, On normal mode this grants The Wafer effect, causing all damage to do a maximum of half a heart each time, Sets your health to 6 hearts if you have fewer than 6. 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